Kesimpta reviews reddit. So others may need to do the pre-meds longer than I needed.

Kesimpta reviews reddit First loading dose at 11:00am even though most people seem to take at night I opted for early in case any situation arose I I start kesimpta on Tuesday, it’s only a couple years old but so far it has one of the highest efficacy rates. It’s a personal choice, and I chose to go with Kesimpta. Clinical trial data have I opted for Kesimpta because I’m older and Kesimpta/Ocrevus show some benefit in progressive disease, which I might be more likely to convert to because of my age. I’m a 39yo M turning 40 in Feb. You don't have to do this. It keeps the b cells Been on Kesimpta for 7 months. Also, make sure that your prior appeals were decided by a neurologist. I was diagnosed almost 2 years ago at the age of 68 and my "brain fog" has also increased. reReddit: Top posts of September 6, 2022 . 51% of reviewers reported a Kesimpta works for me; I like having the control of doing the injections myself, it is quick and easy and I am well supported by both my GP surgery and MS team. They are typically paid for differently, with Kesimpta being a pharmaceutical benefit and Ocrevus often being a medical benefit (because it’s an infusion). Taking an antihistamine ~30 minutes before injecting is a popular recommendation. I don’t mind needles and doing it from the comfort of home, once a month, works for my lifestyle. Recently I switched from Ocrevus to Kesimpta. hello everyone! 22f here, diagnosed about 6 months ago and about to start mavenclad or kesimpta. Tysabri uses a different mechanism - it is believed to prevent b and t cells from crossing the blood-brain barrier by modulating them via a4b1 integrin. Kesimpta and Ocrevus are essentially the same medication but Kesimpta is more effective as you get it once a month rather than every six. My husband just started Kesimpta. So kesimpta is a once a month shot that you give yourself rather than every six months like ocrecus. On Kesimpta website, they say: Store KESIMPTA in a refrigerator between 36°F to 46°F (2°C to 8°C) If needed, KESIMPTA may be stored for up to 7 days at room temperature, up to 86°F (30°C ) If stored below 86°F (30°C), unused KESIMPTA may be returned to the refrigerator and must be used within the next 7 days. At times, the needle for the IV had to be repeated multiple times by the nurse and hurt so bad. I also felt pretty wiped out for a few days after infusion. So this will be shot #5 overall. I take Kesimpta. I’m on Kesimpta, switched from tecfidera. So each spot got hit every 18 or so days. Also, it will likely barely work now that I am on Kesimpta. My Ocrevus crap gap was mild and started about 3 weeks before the next infusion. I just take the syringe out of the fridge, let it warm up on the table for 20min, alcohol swab and inject. the nurse said that ocrevus was a MASSIVE dose every 6 months so you get worse side effects, but kesimpta is a monthly dose which is easily handled with the same efficacy Reply reply Kesimpta for Multiple Sclerosis User Reviews. Lemtrada has 0. Kesimpta is FDA approved, so most private insurance has to cover it. I’ve heard wonderful reviews about Kesimpta so Kesimpta basically binds itself to the B cells and weakens them so they in theory don’t cause anymore demyelination. My appointment with my neurologist isn’t for another month but I’m hoping these lesions aren’t too new and were possibly formed from the period of time I wasn’t on Kesimpta. I got the first dose before starting Kesimpta, and am due to get the second dose. Just ordered my next Kesimpta monthly shot. Also, kesimpta is fully humanized so it’s better tolerated. I started treatment with Kesimpta and used the Bridge program and was able to stay on it for a year while my neurologist fought w my insurance. Also we will try to get pregnant in the next few years and while Mavenclad prevents pregnancies for like 2 years, it cool after, whereas Kesimpta (or Ocrevus) are "forever" and you need to halt treatment and wait 6 months to get pregnant, so you don't really save time in our view. 1 - there aren't many On Kesimpta since July I believe. I chose it because I do not have to go to an infusion center and risk a potential exposure to Covid. All of the symptoms are there - sneezing, coughs, wooly head, tickly throat. Ocrevus is the only DMT currently approved for PPMS. My psuedoexacerbations last longer than 24 hours pretty consistently. My neurologist didn’t mention any “risk of secondary malignancies” when we discussed this, but Kesimpta is a pretty new drug so I’m not sure if this has been looked into at all. I think that the fatigue is finally starting to taper off a bit. I’m already signed up with the “Bridge” program that will ship meds to my home while waiting for insurance coverage for up to one year, but I just found out yesterday that my insurance will not cover Kesimpta (and nor will it cover Ocrevus, which was the other option I believe you, and I don't doubt that your specialist recommended those particular medications. Ocrevus seemed to be causing colitis that resulted in a loss of 40lbs. This is my first DMT and I’ve only known I’ve had MS for 6months. Since OP is not yet on kesimpta, live vaccines are fine. It looks like Ocerevus has a very low chance of breast cancer risk associated with it (<1%) but I'm a still a little hesitant because my mother had breast cancer. I began my first DMT of Mayzent in March of this year, 2020. According to the kesimpta nurse I spoke to, lessening of side effects over time is Hello! I started kesimpta 7/7, when I came home from my nurse assisted first dose I started feeling a bit unwell, then came the flare like symptoms such as extra tingly hands, extra stiff legs, extreme extreme fatigue & even my eye started to act up a little (dx was discovered by optic neuritis in mar/apr. The positive is that Ocrevus made me feel more energetic and capable. Ocrevus is dosed at 600mg/6 months, intravenously while Kesimpta is given as a 20mg dose monthly, via auto injector Ocrevus and kesimpta are very similar; however, kesimpta won’t bring your immunoglobulin levels down as much as ocrevus, which we could say makes you ‘less immunosuppressed’ (?). Basically it works similar to ocrecus but they’re finding that some people develop lesions just before their next dose of ocrecus. The days I take Kesimpta I don’t plan around at all. Today is my second of the weekly ramp up of Kesimpta. Find 3 user ratings and reviews for Kesimpta (ofatumumab) on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction. Posted by u/Soggy_Log_735 - 2 votes and 4 comments I started Kesimpta a little over a month ago and did not have any severe side effects like this. Kesimpta has an average rating of 6. Need some good strong advice. Like another has said, Alongside Kesimpta is fantastic to work with and are extremely professional. When choosing between the two we went with Keisimpta because I have tiny veins, and during both my hospital admissions before starting Kesimpta my IV for the steroid had to be changed daily. 22. I woke up at around 2:00 a. I hope you choose to post about your experiences. I haven’t needed much by way of little tricks to ease the side effects before but I’m getting to that point. The loading dose was rough, but I’m sure that’s the same for Ocrevus. I’ve pretty much known I’ve had MS for about 8 years but it’s only recently been formally diagnosed by MRI and lumbar puncture. I’m lucky. I barely feel anything with Kesimpta and I say this as someone who has a fear of needles. I didn't want it to impact my work or focus, and I don't get weird with Kesimpta. If however you start on Kesimpta and something happens where you have to change, between now and that unknown date in the future you may become JCV+ , and then Tysabri is off the table. If at some point you become JCV+ you can switch to Kesimpta. Best of Kesimpta kills your B cells so that you can’t make new antibodies, so vaccines will be less effective and you’ll be more likely to catch a bug right after you had it. Basically, figure out which injection site works best for you— I learned my I was on Kesimpta for only 9 months, it did wonders for my constant back and hip pain, but I had to come off it due to various recurring respiratory infections; please don’t be put Kesimpta for Multiple Sclerosis User Reviews. I’m at the point of having to decide on possible treatments and think that Kesimpta sounds like a decent fit for me. This is one of a series of personal stories about all Then I put the Kesimpta into a sharps container (there are no exposed sharps), and continue to go about my day. Kesimpta? Treatment A little background: 33F newly diagnosed after an episode of diplopia a little over month ago. TL;DR: I googled kesimpta for months before actually getting to use it, looking for user reviews, and I realized two things. Kesimpta has been a life changer!! Been on it since Sept 2021. Have received both a good brochure about Kesimpta and a diary I shall be filling after each injection. m. In the middle of my tenure, i decided i couldnt handle the arms anymore, so i was down to 6 spots. I think they’re about the same efficacy wise. Have been on it Started on Kesimpta last fall and besides the initial loading dose it’s like I’m not even on a DMT. New to Kesimpta too! Dose #1 was definitely the hardest. I just started Kesimpta and the headaches and nausea are the most prominent symptoms. I’ve been on Kesimpta since February and overall it’s been great! I didn’t really have any side effects from the medication and has been a really smooth start. Pretreat simply means giving meds before the injection to help with any possible side effects. The transfusions are pretty rough for me and I have muscle aches, flu like symptoms for 3-5 days after treatment and the crap gap leading up to next treatment isn'tfun either. Very mild. Moved over from aubagio when upgraded from rrms to spms. The side effects hit for me around 6 hours after injection, so if you can time it before sleep, that helps too :-) After my loading doses I have no It’s just that you really need a informative derm or this Reddit page to help you with bringing tret into your life. i know this isn’t exactly the answer you’re looking for but i chose Kesimpta when given the option between the two simply because i didn’t want to get an infusion. Have to blame the internet for all The reason I have gone into all this detail is because I will be switching to Kesimpta. After that? However, she also mentioned that Kesimpta doesn’t bring down your immunoglobulin levels as much as ocrevus. Some people report feeling better on their DMT, but those are largely anecdotal reports. I could be wrong, but I don’t think they just send it for free without you having insurance and showing your insurance won’t cover it, either. I recently started Kesimpta and prior to my first loading dose, I reviewed your list and actually asked both my neurologist and a Homescripts pharmacist whether I should take more than one antihistamine (I have a history of anaphylaxis) and they each mentioned that the combination Definitely been my experience on Kesimpta too. Aleve worked for a few hours, but now I'm back to feeling like crap. Now i just get fatigued 4 or 5 hours after the jab which lasts through the next day. Kesimpta manufacturer reimbursement. As for Kesimpta being a shot, keep in mind that after the first 3 weekly loading doses, it's only once a month. Just a little background first. I have a full time job that does require me to be on my feet, some days it Hi I’m so sorry UTI’s are so terrible but 1,000x worse when they are literally holding you back from starting the meds you need! I have taken cranberry pills in the past to help with UTI and recently found an article about D-mannose powder that is supposed to be even better than the cranberry. I know the concept of hitting back hard and early, but I am also worried taking an immune suppressant. The leg doses of kesimpta are overkill. Gaming In my view, you should consider that with MS, you can not (yet) repair the damage it causes. talked to my neuro and he said it’s very common to experience a little bit of flare up The post is to everyone who is starting their Kesimpta anytime in the future. If I were your age I probably would have picked Tysabri instead because it doesn’t suppress the immune system in the same way (can’t make new antibodies well on Kesimpta). EVERY BODY REACTS DIFFERENTLY. Kesimpta is the same mechanism of action as Ocrevus, but it is not the same. Both DMTs are considered to be on par with each other and the main differences are the administration (infusion vs subcutaneous injection) and timing. I am fortunate enough to be able to run despite MS and have run 5 miles just prior to Kesimpta and on other occasions, just following Kesimpta. I started Kesimpta Oct 2021 and my 6 month follow up shows 3 new brain lesions. If you need help covering the cost or need to find out if Medicare will cover it, the co-pay assistance team at Genentech has been super helpful, they can’t give you money while receiving government assistance like Medicare but they can help The only side effect I had during the loading doses was a teeny tiny headache in the morning once. Hope it will work for and chances are it will. After multiple appeals denied by my insurance and my year of free Alongside Kesimpta coming to an end in December, I'm exploring going on Ocrevus. This is one of a series of personal stories about all Kesimpta reduces vaccine effectiveness, and makes you ineligible for live vaccines like yellow fever. Many insurers use staffing companies to review the prior authorization appeals, so a lot of the decisions are made by family Hi. Novartis provides a "credit card" to the pharmacy which negates that cost. Right now I’m leaning toward Kisempta. I'm aware of HSCT but haven't done any review of the trial results. Kesimpta works for me; I like having the control of doing the injections myself, it is quick and easy and I am well supported by both my GP surgery and MS team. On the whole it’s been fine, but the last few months every time I have my shot, I get really bad cramping in my upper stomach, and awful nausea to the point I’m throwing up. More posts you may like r/tretinoin. Let me just tell you that kesimpta was the best medicine I've received up till now. As expected, I had chills, fatigue and tiredness for a few hours shortly after taking the first injection. I hope Kesimpta gets Kesimpta is so easy. P. Wondering if it could be a side effect of Kesimpta. Dosage, mode and route of administration, contraindications According to a clinical trial comparing Kesimpta (ofatumumab) to Ocrevus for the treatment of relapsing forms of multiple sclerosis (RMS) in adults, the main difference is cost Careful review of my medical records shows my first attack at age 22 was misdiagnosed, as were all the other attacks for the 23 years in between. So, I finally started taking Kesimpta (insurance appeal is still pending unfortunately). It takes me about 2 minutes a month. Rebif had a site reaction each time. I have now known about my MS for 11-1/2 years. I took my second dose of the loading doses last Friday and had no issues other than I It's also such a long infusion so I was considering switching to Kesimpta, but then my neurologist told me about Briumvi and it sounds promising. Kesimpta for Multiple Sclerosis User Reviews (Page 2). Three weeks ago, Home Scripts had the three doses delivered to my door. It's only twice a year but I'd prefer doing it at home monthly compared to the big deal infusion days are. If this KESIMPTA is not Kesimpta just seems more convenient; I have to drive an hour and a half to get infusions and it takes up a whole day. Everything about Kesimpta has been completely wonderful. It turns out having a steady supply of meds in the body can be better than a massive dose that trails off over 6 months. Kesimpta doesn’t do anything about the lesions you already have; they will resolve or not. S: It’s awesome to see how the most recent therapies are more and more effective. Allot of us are on kesimpta, so I'm sure you can find some help here. I hope switching to Kesimpta helps with your side effects. Not gonna lie, the first dose of Kesimpta was brutal. I'm the same as you on the shots, but it looks like Kesimpta comes with auto-injectors which means I jab a thing against my leg and it pokes for a few seconds then goes away. Live vaccines are only contraindicated when on an immunocompromising drug like Kesimpta or Ocrevus. My 1st medication was copaxone 11ish years ago. I think Kesimpta and Mavenclad are the closest ones with 0. 3 loading doses and my second monthly. (Hair loss, Thoughts of a Kesimpta User! TLDR— If you do not want to read all, at least please read the first 2 paragraphs ️. I have had a lot of additional fatigue since starting Kesimpta, and I had headaches for the first few weeks. I will do some research into the crap gap. Injection does not hurt at all. I used Rebif from 2009-2011, and Kesimpta shots are not even close to being as difficult -- both in administering and in tolerating. Plegridy is another one, but they work differently and are considered to have different "efficacy" (= how efficiently the medication can prevent relapses in people with MS) as well as different potential side effects. From what I've gathered so far, Kesimpta and Ocrevus may have better success metrics, but my husband is still leaning Mavenclad due to the potential to be off a DMT after the two bouts of treatment. Always take premeds before every shot (I just did shot 13); 2. I had a cold in the summer, it took about a im moving onto kesimpta. 9 out of 10 from a total of 65 reviews for the treatment of Multiple Sclerosis. The Phase III Never a problem to ask a question. Not to minimize the impact of COVID in anyone (because long COVID can impact anyone, is no joke, and can hit you even if you have a mild acute infection)but one thing you always need to keep in mind with studies/data review like this is “who is in the group”. That said, most people either notice nothing or get a cold a couple more times a year. Or have been due for a year, basically. But, they can request you start with a generic or insurance recommended medication first. 51% of reviewers reported a positive experience, while 18% reported a negative experience. Home ; The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may Kesimpta is only a monthly leg shot because that's how they did their trial. I yet have to speak more details over Kesimpta with my doctor but I would like to hear the verdicts of others whom are on Kesimpta. Apparently ocrevus brings them down a little bit more. I pay absolutely $0 per dose for my Kesimpta. This morning I noticed that both eyes have broken blood vessels. I hit a nerve the last time I did my shot and it was incredibly painful, and I have a high tolerance for In August 2021 I was notified my insurance is now paying for Kesimpta -- except $88 a month. As shitty as I felt for those months I feel back to my normal self now. I failed to mention, if you choose Kesimpta, please ask about premeds, especially for the first shot. In all actuality, the neurologist should be watching the b cells to determine when the next dose should be for ocrevus rather than every 6 months. I think that because I'm 57, and my list of allergies is as long as your arm and some are pretty severe, my doctor has me do so out of an abundance of Kesimpta is like Tysabri in that it has a similar dosing schedule (28 days), but much easier! Kesimpta works similarly to Ocrevus in that both are B cell depleters. Today has been a flurry of phone calls between the advocating department of my doctor's office and Novartis' Alongside, which offers a Bridge program to provide the med for free while awaiting insurance coverage. Kesimpta has a really good copay assistance program (through Novartis), but I think you actually have to have health insurance. My first dose was the expected flu-like symptoms and I felt like I was hit by a bus. 1. I am fairly sure I'm coming down with a cold. (Rebif killed my liver in a little less than 2 years, so I had to stop it). I kinda feel like it doesnt. Kesimpta is the newest and easiest, FDA approved in Aug 2020. Since then I've been on copaxone Just started Kesimpta today, so relieved to finally be on something! Was diagnosed in January 2021 so all still pretty new to me. Posted by u/naturaloccurrence - 2 votes and 2 comments I've been on Kesimpta for 9 months and the last few months I also have been experiencing "crap gap" around a week before my next dose. Hey folks! I'm on Kesimpta, and I want to go to dentist to try to do some dental work. 9 ARR respectively. I’ve been on Kesimpta since April and had no problem with my pot use when I started, but since then (in the last couple of months) I’ve noticed that pot is spiking my heart rate significantly like panic would, even if I go to sleep right after an edible. Get any vaccine you think you might need in the future. Also this is the first drug that gave me a stable MRI. There’s A big reason I chose Kesimpta is to avoid the "crap gap" of like 4-6 weeks of feeling hellish before the next Ocrevus infusion. JC virus is generally not a concern with Kesimpta, but your doctor may monitor your JCV titers over time. The best advice I can give is use the Tylenol, stay hydrated, and exercise once you’re feeling better. Kesimpta administration has no impact, no muscle pain, nothing. Hopefully you aren’t JC+ and your results come in soon, it’s a long wait from Denmark hey I’m glad he mentioned kesimpta as an option, I wasn’t sure if aussie neuro’s were onboard with it just yet as it only came out not long ago, I hope my neuro will consider it an option for me too. I was at a wedding a couple of weeks ago and I think I picked something up there, or maybe the grocery store or from my roommate- who knows. The Real Housewives of Atlanta; The Bachelor; Sister Wives; 90 Day Fiance; Wife Swap; The Amazing Race Australia; Married at First Sight; The Real Housewives of Dallas It seems to come in waves once the worst is over. With Ocrevus, I lost half a day twice a year. I've had no relapses while on Kesimpta. The bad: Lots of side effects in first 3 months. . Im Just adding my 2 cents/experience. It’s that easy. I previously had a relapse mid January that threw me off a bit and about 2-3 weeks after the initial onset I started the remission process. Personnely I had chills in the night the first dose but was back to 100% by next morning. Reply reply More replies More replies I switched from Copaxone to Kesimpta, and I took my first shot last night. " I can't find anything that goes deeply into their specific similarities and differences. I wanted Kesimpta so I did not have any potential Covid exposures from being at an infusion center, nor from the 1-1/2 hour drive to/from the facility (including potty breaks). That sense of safety works better for me. I've been on Kesimpta since the study started in Europe (like 5 ish years back). Spms and kesimpta here. Mostly read about loading dose (usually first only too) being a pain with fever, chills, etc - all listed symptoms on the Kesimpta page! After that, seems like most people are fine. But doing steroids 2 times a year for however long worries me about the long term side effects and Kesimpta would help me avoid that. As far as I have read it has the same effect - depleting B-Cells. I was diagnosed in February of 2020. Hey everybody. Skip to main content . I am sharing my experience here : Before starting kesimpta, I read about the side effects in this here. Compared to that kesimpta is a cake walk. Any insight is appreciated. Simply my documented experience for those researching. I would also opt for Kesimpta instead of Mavenclad. Two major differences: Ocrevus is mostly humanized while Kesimpta is fully humanized - this means far less chance of reactions to the medication itself on Kesimpta . Right now I'm between Ocerevus and Kesimpta. Interestingly, the rate of breast cancer in the comparator was Lemtrada is not like Kesimpta. I switched from Ocrevus to Kesimpta this year because my new insurance didn’t want to approve Ocrevus. my question : has anyone got any recommendations for which one is best ALSO anyone got any Reddit iOS Reddit Android Reddit Premium About Reddit Advertise Blog Careers Press. A bit more tired than usual, and a little bit of nausea for a while, but peppermint tea helped a lot. Been on it for 2 years not with zero side effects. Kesimpta is very similar to Ocrevus and uses a very similar underlying mechanism (b-cell depletion by lysing all CD20 bearing b-cells). I've tried to do some research on the cancer risks associated with Kesimpta, but I can't find much, presumably because the drug is so new. Reviews for Kesimpta Kesimpta once a month so far is about easy as I could imagine, tbh (even 2/days Tecfidera pills I found more inconvenient) My understanding is Kesimpta (particularly following taking the treatment), I'm more prone to new infections (repeat infection shouldn't be an issue), so get your vaccinations the couple days before the shot. I only experienced intense muscle aches and I was FREEZING for a hours. Kesimpta: Never have an injection site reaction. Find 3 user ratings and reviews for Kesimpta (ofatumumab) on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Kesimpta: Learn more about this medication and give your opinion. This is my first cold I was diagnosed about 2 months ago and have recently started high efficacy treatment with Kesimpta. Doctor told me to change from abaugio to kesimpta. Kesimpta is among the best drugs in the world for MS. I felt crummy after 2 and 3, and same as usual after the first monthly dose. This one is just especially funky as I don’t usually have the minor headaches (which I didn’t think was an MS thing) and seemingly real mild almost vertigo. I also want potentially to make a bridge or implants in some place where I have missing teeth. I did my loading doses of Kesimpta in Feb and it went really smoothly for me, but I definitely recommend taking a tylenol with the loading doses to manage headache, fever/chills, unwell feelings. Not a single side effect to speak of. Same- diagnosed in January and started Kesimpta in March. My first dmt ever. 9 out of 10 from a total of 71 reviews on Drugs. However today he brought up to switch to Kesimpta. Maybe that's the issue - I'm having a hell of a time deriving actual numbers. ive had little to no side effects with kesimpta but everyone is different. From what I've heard it's a fairly new drug from Novartis, and that it's very similar to the way Tysabri works except that it The first injection I got flu symptoms that my multiple sclerosis nurse had explained and had to take paracetamol (tynol/panodil) every 4 hours for the first 24 hours. 10 ARR and 0. With Kesimpta, I have had no side effects after completing the loading doses. I think the biggest heads-up I would give him is for the night after his first injection. I opted not to do it so I could start the dmt sooner. Especially compared to 2009 through 2011 when I used Copaxone and Rebif. The main concern with JC virus is it has lead to PML in patients on other anti-CD20 therapies, namely rituximab. Bonus: Kesimpta is Welcome, Kesimptian who starts on Wed. The first dose was the worst for me - flu-like symptoms kicked in 12ish hours after the injection and lasted about 24 hours. Rebif was a flu feeling that never ended. Felt like the flu. So with Kesimpta I would bit a little bit less immunodeficient than with Ocrevus, you could say. There are medicines that can help lesson some of the symptoms MS folks get, and these differ depending on what the symptoms are, but Kesimpta will not do anything to directly cause your symptoms to improve. Reply reply Top 1% Rank by size . I read horror reviews on these drugs and some ppl reporting that the drugs made their symptoms worse. Plus, it’s taken monthly thru a SC injection which takes me about 15 seconds to get it done. The swab/injection take about 15seconds. During my own research I thought Kesimpta seemed prefereable but I also understand the Tecfidera recommendation. with body aches, chills, and sweats, just like I used to get from Avonex. i’m edging towards mavenclad as i live a very nomadic lifestyle so it seems the most flexible but not sure as i originally decided on kesimpta before they told me about mavenclad. But honestly, I'm not ready to throw in the towel on B cell depleters yet - for the simple reason that I was fortunate enough that my relapses were not very severe. Has anyone stopped taking kesimpta and what happened? Re: B-cells. I was his first patient on it, plus the first patient in my state using it. Thus far ive had no side effects other than the achy stuff during the beginning dose. com. After ~6 months, one possibly two Super easy, almost no pain shot once per month. ) Just came here to say that Kesimpta (Ofantumumab) has the greatest potential in my oppinion in terms of effectiveness, side effects and minimal disruption. I chose Kesimpta because I have a busy life and didn’t want to spend 4 My neuro told me prior to starting Kesimpta I could get YF, but recommended I delay kesimpta for 6 weeks post injection. Thanks. Any advice? I use ginger, Zofran, cbd, eye masks, ibuprofen, Tylenol, etc. It sounds pretty rough to have to repeatedly go through that. I had 95ish infusions of Tysabri and it served me well. I had hyped up my first injection (as some have had flu-like symptoms) but it really was painless and super easy. 26, Ocrevus 0. I plan on getting my CD19/20 test done at the beginning of March '23 just to be very sure. Not intended to scare away. I can chose between Tecfidera and Kesimpta. I'm a 29 year old guy, I was diagnosed with MS when I was 24 after getting optic neuritis in my left eye. I keep putting it off, with my neurologist's support, because for one thing it suuuuuuuuucks as far as side effects and wiped me out. With Lemtrada both B and T cells are wiped out with 5 consecutive days of infusions, then nothing is done until a year later when another 3 consecutive days of infusions are given, once again wiping out B and T cells. Three weeks later, my antibody test showed a "robust response," to quote my doctor. So ultimately a very personal choice for you My neurologist at first recommended Tecfidera. The first injection gave me a few hours of side effects like chills and body aches, but I haven't had any since. Where in the world are you from? By the way, Kesimpta is my 5th MS-medicin. Hey all I have kesimpta delivery tomorrow. After that I have had no reaction. So I was prescribed Kesimpta the last week of April, the reps for Kesimpta are incredible. They just have a different delivery method (Kesimpta is a monthly epi-pen style shot while Ocrevus is an infusion once every 6 months) and Kesimpta is a fully humanized monoclonal antibody whereas Ocrevus is a mostly humanized monoclonal antibody. I’ve been on it for nearly a year with no issues, may even be lucky like me with no loading dose symptoms! 😄 After an earlier discussion, I told u/editproofreadfix I'd share how my first 3-dose weekly induction to Kesimpta went, so here I am. Time: Kesimpta takes a few minutes out of my day once a month. Also Kesimpta doesn't require the premeds that Ocrevus does. It crept up on me about 5-7 hours after I took the shot. With kesimpta if i get an infection or something i can always delay the dose and i feel more in control. (50% to 47%. My first dose landed me in the hospital with severe muscle pain in my back. After 5 months of kesimpta, the loading doses were the worst for me with fever, chills and general 'flu like symptoms'. I'm using kesimpta for almost a year now as my first DMT and it's working well for me. I can’t recommend Kesimpta enough. When i was on rebif, i did 3 shots a week in 8 potential spots. I was planning to switch to Kesimpta anyway before the relapse but the main motivating factors were Id make sure to review all this with health care provider before taking next dose. Kesimpta: No flu-like feelings. Did the loading doses and took his 1st monthly dose 2 weeks ago. He hasn't been sick, isn't tired, hasn't done anything to cause this. Kesimpta (or Ofatumumab) is a DMT - a disease modifying treatment for MS. On Kesimpta since Feb 2023, I feel exactly the same as when I was not on Kesimpta. Been on Kesimpta now for around 2 years. Hopefully it's not so pronounced with Kesimpta. Tips: alternate legs with each injection (for example: loading dose #1 in right leg, loading dose #2 in left leg, loading dose #3 in right leg, maintenance dose #1 in left leg, maintenance dose #2 in right leg etc etc), after injection wait 20 seconds before removing the pin to make sure all Kesimpta is the same mechanism of action as Ocrevus (both are anti-CD20 meds, with very similar efficacy). Don't know if this is the Kesimpta or age related. Every posts that I read had horror stories. 12 shots a year is infinitely better than 700 pills plus flushing and stomach issues immediately after. and dry skin so bad it resulted in skin flaking away and crusty lips. Hi, I have a couple of questions about kesimpta for anyone who is currently taking it. I think im lucky to have been approved for a high efficacy right off the bat but I have a question that I cant find any answers for. Internet Culture (Viral) Amazing; Animals & Pets The rate of breast cancer in the Kesimpta arm was consistent with what you would see in the general population. Now I have 2 concerns: Is it risky (infections and stuff) due to me being on Kesimpta? Tysabri. • Write the date taken out of the refrigerator in the space provided on the carton. I was under the impression (thanks to the pharmacy care team) that side effects with Kesimpta are Kesimpta has none of those problems. With Kesimpta I don’t always get a New data reveals that more relapsing multiple sclerosis (RMS) patients continuously treated with Kesimpta ® (ofatumumab) had no evidence of disease activity (NEDA) versus switching from teriflunomide. Before that I've tried copaxone and aubagio. So when Kesimpta became FDA approved in August 2020, I pushed my MS Specialist hard to take it. The first dose knocked me out for a day and half. Only take Kesimpta during his office hours (probably because I live in a rural area 1-1/2 hours from his clinic, and he wants to personally talk to the local docs if need be; this has absolutely never occurred). MY KESIMPTA EXPERIENCE: My MSS (MS Specialist) has two requirements: 1. Kesimpta has left me with crushing fatigue. Kesimpta starts with a loading dose of one shot a week for three weeks; then one week of Posted by u/Rex641 - 2 votes and 3 comments I was vaccinated without stopping or changing Kesimpta dosing. Took my first dose and was horribly sick that night (chills, sweats, dizziness). Kesimpta has their Alongside and Bridge programs that will cover your prescription costs up to Reddit iOS Reddit Android Reddit Premium About Reddit Advertise Blog Careers Press. I’m a mostly fit and active 53-year old for whom MS is currently more of an irritation than a disability. They work to prevent future attacks and damage, but they don't do anything for existing damage. I am on Rituximab and hoping to switch to Kesimpta when it is approved in my country. I don’t know what to do or choose. Kesimpta is easy to administer and while I am nervous due to some IPIRs I experienced on Copaxone, it really is nothing to inject Kesimpta. Question - for those on Kesimpta can you drink alcohol? Talked to a pharmacist and she was kind of wishy washy about it. took til January to feel normal again. Maybe all in my head but hey whatever works unh! The injections are super easy and no days of work missed for infusion Im happy with the switch Reddit . Get the Reddit app Scan this QR code to download the app now. There's one tooth that needs healing/fixing if possible. That being said, I have had several doctors tell me Ocrevus and Kesimpta are "basically the same drug. Mavenclad (2019), Kesimpta (2020), and now Briumvi. 15, an Tysabri 0. The Kesimpta injection that lasts 20 seconds is easier than the 5-6 hour IV. Thank you for sharing that. So others may need to do the pre-meds longer than I needed. But it can prevent new lesions from happening. I'm on Kesimpta for 10 months now - you'll be totally fine after the first 3-4 doses! For me it wasn't so bad, I just felt a bit drowsy and had some body aches almost immediately -like 2 minutes after - and had trouble waking up the next morning, but after the 4th month it never happened again. Is there some test similar to the CD 19/20 for kesimpta that checks the Posted by u/croc-hop - 5 votes and 14 comments I came to Reddit a while ago with the same debate. I don’t even experience itchy angry welts like Copaxone! I did have a rough 7-36 hours after the 1st loading dose. Plus with Briumvi being so new that worries me too. Kesimpta is an MS therapy that is believed to work by depleting B-cells, a type of immune cell involved in the inflammation that damages the nervous system in MS. I have a 4 month old baby that I am currently breastfeeding, and my husband and I would definitely like to have one more baby in the not so distant future. yes it is only every six months, while kesimpta is a shot every month, but an infusion just seemed a bit scary and “intense” to me lol. I would highly encourage you to look at the drugs more closely. But before we get to that part, I have medicaid, and it took me four months to find a doctor that would prescribe me something that wasn't Copaxone and give me something with a better efficacy rate. Just administered this morning. • If stored below 86°F (30°C), unused KESIMPTA may be returned to So, Kesimpta isn't meant to treat symptoms-- most DMTs aren't. So yes, you can get it. Now I am a bit unsure which one to chose. Sure, it lowers your immune system a Get the Reddit app Scan this QR code to download the app now. First dose was in September last year. My neuro has okd the switch to KesimptaIm worried about side effects (have read some pretty negative reviews). Last Saturday was the third of the 3-dose introductory cycle for Kesimpa. After recently learning that I’ve failed Tecfidera, I made the decision with my neurologist to switch to Kesimpta. Insurance denied Kesimpta. They are seriously the absolute best people. Now I was on Ocrevus previously, which is very similar to Kesimpta, so after the loading doses, I no longer needed to pre-dose with Tylenol/Benadryl. There is a reason you must take it every month. I bring this up because my doctor has to specifically write to my insurance that Kesimpta was my best option due to my veins. So thats how its fda approved. Kesimpta could be done as an infusion like ocrevus. However, there have been no Posted by u/Dense_Pick_6215 - 5 votes and 7 comments I was briefly on Ocrevus last year then switched to Kesimpta(free through drug manufacturer for a year) when my new insurance denied the Ocrevus treatments. Or check it out in the app stores &nbsp; &nbsp; TOPICS. However, while you can argue that one little injection every 4 weeks is more convenient than an entire day lost getting the IV you could also frame it the other way around. One thing mentioned is that there is some evidence to suggest Kesimpta is slightly more effective at reducing relapse rate. Has anyone switched to Ocrevus to Kesimpta. Reading this sub, it's about 50/50 whether or not a person's doctor has them pretreat before Kesimpta. Something I noticed pretty quickly is that my eczema, which I had as a teenager but has been mostly dormant for going on 10 years, has come back with a vengeance since starting Kesimpta - I admit it could just be coincidence though! It seems to get worse in the week after taking my Kesimpta, but it can flare up at any point. Lemtrada is an immune reconstitution therapy, not a continuous DMT like Kesimpta. It was not a horrible experience in my opinion. throughout that whole year, my neurologist tried at least 4 times to get my insurance to cover it but they said no each time and said smth similar about trying a less effective drug to make sure that didn’t work for me (aka another relapse!!!) • If needed, KESIMPTA may be stored for up to 7 days at room temperature, up to 86°F (30°C ). Allot of kesimpta users (including me) have a flu like reaction. mostly because anyone taking it is still on it. Cleared up by about the 6-month mark. ilwbmy afcy wmpxruz qanuh hsdgw ynaioudr its mgkzei vxdij mpm